Key Points
- Fowl cholera is a contagious bacterial disease affecting poultry, caused by Pasteurella multocida, with research suggesting it can lead to high mortality in acute cases.
- It seems likely that the disease spreads through direct contact, contaminated feed, and wild birds, with evidence leaning toward stress and poor conditions increasing risk.
- Prevention may involve biosecurity measures, vaccination, and good management, though effectiveness can vary.
- Treatment options include antibiotics like sulfonamides and tetracyclines, but the evidence leans toward challenges with resistance and residues in meat and eggs.
Fowl cholera is a highly contagious and often deadly disease that strikes poultry and other birds, causing significant challenges for farmers worldwide. This bacterial infection, triggered by Pasteurella multocida, can lead to massive economic losses in the poultry industry if not addressed properly. It can present in acute or chronic forms, with the acute form often leading to sudden death and high mortality, while the chronic form causes localized infections like swollen wattles or lameness. Whether you’re a poultry farmer or just curious, this guide will equip you with clear, actionable insights.
Etiology
Fowl cholera, also known as avian cholera or avian pasteurellosis, is recognized as a major infectious disease in poultry, with historical significance dating back to the 18th century, notably studied by Louis Pasteur in 1880. The causative agent, Pasteurella multocida, is a gram-negative, non-spore-forming rod with 16 somatic serotypes and five capsular serotypes (A, B, D, F), with serotype A being most commonly isolated in poultry cases.
Susceptibility to Fowl Cholera
Which birds are at risk? Fowl Cholera mainly targets domestic poultry like chickens, turkeys, ducks, and geese. However, it doesn’t stop there—it can also infect wild birds, pigeons, and pheasants. Among poultry, turkeys are especially vulnerable, often suffering more severe symptoms than chickens. Knowing which birds are susceptible helps farmers take extra precautions with high-risk flocks.

Clinical Signs of Fowl Cholera
The symptoms of Fowl Cholera vary depending on whether the disease hits in its acute, chronic, or localized form. Recognizing these signs early can make all the difference in controlling an outbreak.
Acute Form
The acute form strikes fast and hard. Birds may drop dead without warning, leaving farmers shocked. When symptoms do appear, they include:
- High fever
- Loss of appetite
- Ruffled, messy feathers
- Slimy discharge from the mouth and nose
- Greenish diarrhea
- Trouble breathing
- Sudden death
This form is especially common in turkeys and can wipe out entire flocks quickly.

Chronic Form
The chronic form is milder and often follows an acute outbreak. It lingers, causing ongoing issues like:
- Swollen joints (arthritis)
- Puffy wattles, sinuses, or head areas
- Twisted neck (torticollis) from ear infections
- Long-term breathing problems
While less deadly, it still hurts flock productivity.

Localized Form
Sometimes, Fowl Cholera stays confined to specific areas, like the lungs, air sacs, or reproductive organs. These cases are trickier to spot but still need attention.
Incubation Period of Fowl Cholera
How long does it take for Fowl Cholera to show up? The incubation period—the time from infection to symptoms—is usually short, lasting 1 to 3 days. However, this can shift depending on the bacterium’s strength and the bird’s health. A quick onset means farmers must act fast when they suspect exposure.
Morbidity and Mortality in Fowl Cholera
Fowl Cholera spreads like wildfire, with morbidity rates (the percentage of birds getting sick) often hitting 100% in unprotected flocks. Mortality rates (the percentage that die) depend on the disease type and how soon treatment starts. In acute cases, especially in turkeys, mortality can soar to 50-100%. Chronic cases have lower death rates but still cause losses through poor egg production or the need to remove sick birds. These numbers highlight why early action is critical.
Pathogenesis of Fowl Cholera
How does Fowl Cholera wreak havoc inside a bird? The Pasteurella multocida bacteria usually sneak in through the respiratory tract—think breathing in contaminated air—or through cuts and scratches. Once inside, they multiply fast and can flood the bloodstream, causing a dangerous condition called septicemia. The bacteria release toxins that harm tissues and organs, leading to the symptoms we see. Stressors like overcrowding, poor diet, or other infections make birds more likely to fall ill. Understanding this process shows why clean air and low stress are vital.
Postmortem Findings in Fowl Cholera
When a bird dies from Fowl Cholera, a necropsy (animal autopsy) reveals clear clues. Here’s what vets often find:
- Red, bloody spots (hemorrhages) in organs like the liver, spleen, and heart
- A swollen, fragile liver with dead tissue patches
- An enlarged spleen
- Lung congestion or pneumonia
- Inflamed heart lining (pericarditis) or air sacs (air sacculitis)
- Abscesses in wattles or joints in chronic cases
These signs confirm the disease and guide treatment for the rest of the flock.
Treatment of Fowl Cholera
Can Fowl Cholera be treated? Yes, but speed is key. Antibiotics are the go-to solution, and options include:
- Sulfonamides
- Tetracyclines
- Penicillin
- Erythromycin
However, some strains resist these drugs, so testing which antibiotic works best is smart. Alongside meds, give birds clean water, good food, and a calm space to recover. Treatment alone isn’t enough, though—prevention is where the real wins happen.
Prevention of Fowl Cholera
Stopping Fowl Cholera before it starts saves time, money, and birds. Here’s how:
- Vaccination: Shots tailored to Pasteurella multocida serotypes can protect flocks.
- Biosecurity: Keep the disease out by limiting farm visitors, cleaning gear, and isolating new birds.
- Sanitation: Regularly scrub coops and tools to kill lingering bacteria.
- Management: Avoid crowding, ensure fresh air, and feed birds well to keep them strong.
- Monitoring: Watch for early signs and act fast—quarantine sick birds and treat them right away.
These steps cut the risk and keep your flock thriving.
Conclusion
Fowl Cholera is a tough opponent for poultry farmers, but it’s not unbeatable. By knowing its cause (Pasteurella multocida), spotting symptoms early, and using smart treatment and prevention plans, you can shield your birds from this threat. Quick action and good habits—like vaccination and clean coops—are your best tools to stop outbreaks and keep your flock healthy and productive. Stay informed, stay proactive, and Fowl Cholera won’t stand a chance.
